BIOPRINTIA - Izertis

BioPrintIA

3D implants with AI for regenerating joint tissues

The main objective of the BioPrintIA project is the industrial research of a new treatment based on the generation of novel cellularised, functionalised, and personalised bioimplants using innovative technologies such as artificial intelligence and 3D bioprinting. This approach aims to enable the transplantation of osteoarticular tissues into the injured area, providing a sustainable solution to current age-related degenerative knee pathologies. It represents an innovative treatment designed to improve patients’ quality of life, reduce their degree of dependency, and contribute to lowering healthcare costs associated with current treatments.

The main objective of the BioPrintIA project is the industrial research of a new treatment based on the generation of new bioimplants

Challenges

To generate 3D implants specific to articular cartilage and tendon injuries through the development of innovative bioinks and the corresponding 3D bioprinting system.

To promote osteoarticular regeneration and the resolution of inflammation and pain through the development of personalised, tissue-specific therapeutic strategies based on stem cell transplantation.

To validate the bioinks and their components in vitro using a novel cartilage and tendon organ-on-a-chip model, and to test the 3D-developed implants in vivo using animal models.

To validate the 3D-developed implants by analysing the results of in vitro and in vivo tests using artificial intelligence.

Solution

The solution to be developed will consist of 3D cellularised implants functionalised with drugs for tissue regeneration and the treatment of osteoarticular degenerative processes. These implants will provide solutions for clinical needs that are currently unmet by existing surgical and non-surgical treatments.